Wednesday, May 16, 2012

This is your brain on sugar: UCLA study shows high-fructose diet sabotages learning, memory

Eating more omega-3 fatty acids can offset damage, researchers say

Fernando Gomez-Pinilla
Fernando Gomez-Pinilla
[Correction: Paragraph 5 of this release was changed from an earlier version to reflect that the study focused on fructose generally, not specifically on high-fructose corn syrup; that while high-fructose corn syrup is sweeter than cane sugar, it is not "six times sweeter"; and that Americans consume approximately 35 pounds of high-fructose corn syrup per capita annually, not "more than 40 pounds." The researcher's quote in Paragraph 6 has also been changed slightly to avoid the implication that the study focused solely on high-fructose corn syrup.]
 
Attention, college students cramming between midterms and finals: Binging on soda and sweets for as little as six weeks may make you stupid. 
 
A new UCLA rat study is the first to show how a diet steadily high in fructose slows the brain, hampering memory and learning — and how omega-3 fatty acids can counteract the disruption. The peer-reviewed Journal of Physiology publishes the findings in its May 15 edition.
 
"Our findings illustrate that what you eat affects how you think," said Fernando Gomez-Pinilla, a professor of neurosurgery at the David Geffen School of Medicine at UCLA and a professor of integrative biology and physiology in the UCLA College of Letters and Science. "Eating a high-fructose diet over the long term alters your brain's ability to learn and remember information. But adding omega-3 fatty acids to your meals can help minimize the damage."
 
While earlier research has revealed how fructose harms the body through its role in diabetes, obesity and fatty liver, this study is the first to uncover how the sweetener influences the brain. 
 
Sources of fructose in the Western diet include cane sugar (sucrose) and high-fructose corn syrup, an inexpensive liquid sweetener. Far sweeter than cane sugar, the syrup is widely added to processed foods, including soft drinks, condiments, applesauce and baby food. The average American consumes roughly 47 pounds of cane sugar and 35 pounds of high-fructose corn syrup per year, according to the U.S. Department of Agriculture.
 
"We're less concerned about naturally occurring fructose in fruits, which also contain important antioxidants," explained Gomez-Pinilla, who is also a member of UCLA's Brain Research Institute and Brain Injury Research Center. "We're more concerned about the fructose in high-fructose corn syrup, which is added to manufactured food products as a sweetener and preservative."
 

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