At the Center for Brain Research at the MedUni Vienna an important
factor for stress has been identified in collaboration with the
Karolinska Institutet in Stockholm (Sweden). This is the protein
secretagogin that plays an important role in the release of the stress
hormone CRH and which only then enables stress processes in the brain to
be transmitted to the pituitary gland and then onwards to the organs. A
current study on this molecular switch has now been published in the
top-ranked EMBO Journal.
"If, however, the presence of secretagogin, a
calcium-binding protein, is suppressed, then CRH (= Corticotropin
Releasing Hormone) might not be released in the hypothalamus of the
brain thus preventing the triggering of hormonal responses to stress in the body," explains Tibor Harkany of the Department of Molecular Neurosciences at the MedUni Vienna.
http://medicalxpress.com/news/2014-11-trigger-stress-brain.html
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